Usefulness of light Microscopy in lymph node fine needle aspiration biopsy

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Liste des auteurs: Egea AS
Gonzalez MAM
Barrios AP
Masgrau NA
de Agustin PD
Editeur: Karger Publishers
Année de publication: 2002
Numéro du volume: 46
Numéro de publication: 2
Page d'accueil: 364
Dernière page: 368
Nombre de pages: 5
ISSN: 0001-5547
Languages: Anglais-Royaume-Uni (EN-GB)


OBJECTIVE: To evaluate light microscopic examination of lymph node fine needle aspiration biopsy (FNAB) in order to determine the indications for ancillary procedures and biopsy.STUDY DESIGN: Reports and smears from 693 consecutive lymph node FNABs were reviewed. Fifty-five cases were excluded because of inadequacy of the material, and another 26 were excluded because follow-up information was not available.RESULTS: Cytologically, 220 cases were diagnosed as positive for malignancy and 392 as negative. Global sensitivity was 94.1% and specificity 96.9%. Sensitivity was higher for nonlymphoid neoplasms (98.2%) than for lymphoproliferative disorders (82.8%).CONCLUSION: Lymph node FNAB is a cost-effective procedure, and with adequate cytologic examination and follow-up, a large number of biopsies and time-consuming ancillary techniques can be avoided.


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