Absolute Power Spectral Density Changes in the Magnetoencephalographic Activity During the Transition from Childhood to Adulthood

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Publication Details

Author list: Fernández A
Publisher: Springer (part of Springer Nature): Springer Open Choice Hybrid Journals
Publication year: 2017
Volume number: 30
Issue number: 1
Start page: 87
End page: 97
Number of pages: 11
ISSN: 0896-0267
Languages: English-Great Britain (EN-GB)


Abstract

The aim of this study was to define the pattern of reduction in absolute
power spectral density (PSD) of magnetoencephalography (MEG) signals
throughout development. Specifically, we wanted to explore whether the
human skull’s high permeability for electromagnetic fields would allow
us to question whether the pattern of absolute PSD reduction observed in
the human electroencephalogram is due to an increase in the skull’s
resistive properties with age. Furthermore, the topography of the MEG
signals during maturation was explored, providing additional insights
about the areas and brain rhythms related to late maturation in the
human brain. To attain these goals, spontaneous MEG activity was
recorded from 148 sensors in a sample of 59 subjects divided into three
age groups: children/adolescents (7–14 years), young adults
(17–20 years) and adults (21–26 years). Statistical testing was carried
out by means of an analysis of variance (ANOVA), with “age group” as
between-subject factor and “sensor group” as within-subject factor.
Additionally, correlations of absolute PSD with age were computed to
assess the influence of age on the spectral content of MEG signals.
Results showed a broadband PSD decrease in frontal areas, which suggests
the late maturation of this region, but also a mild increase in high
frequency PSD with age in posterior areas. These findings suggest that
the intensity of the neural sources during spontaneous brain activity
decreases with age, which may be related to synaptic pruning.


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Last updated on 2019-13-08 at 00:16