Neuropsychology of temporal partial epilepsy: a comparison of drug resistant and pharmacologically controlled patients | Neuropsicología de la epilepsia parcial temporal: comparación entre pacientes farmacorresistentes y pacientes controlados farmacológicamente.




Details zur Publikation

Autorenliste: Maestú, F., Martín, P., de Sola, R.G., Obregón, M.C., Gómez-Utrero, E., Fernandez, A., Sánchez, A., Paúl, N., Ortiz, T.
Verlag: Cesar Viguera
Jahr der Veröffentlichung: 2000
Zeitschrift: Revista de Neurologia (0210-0010)
Bandnummer: 31
Heftnummer: 9
Erste Seite: 817
Letzte Seite: 821
Seitenumfang: 5
ISSN: 0210-0010
Sprachen: Spanisch-Spanien (ES-ES)


INTRODUCTION: Various factors may contribute to cognitive deterioration
in temporal lobe epilepsy, and there is controversy as to which has the
greatest effect. PATIENTS AND METHODS: In this study, we establish a
comparison between patients with temporal lobe epilepsy controlled by
drugs and drug-resistant patients, with the object of discovering the
effect of different factors in causing cognitive damage. RESULTS: The
persons whose disorder was controlled by pharmacological means had
better results in memory and intelligence tests than those with
drug-resistance. The latter had alterations of declarative memory for
verbal material (left) and for visio-spatial material (right) in delayed
free recall tests. Also, the greater proportion of symptomatic
epilepsies in the drug-resistant group affected their greater cognitive
deterioration. CONCLUSIONS: Our results show that having long-standing
epilepsy with great frequency of seizures and symptomatic epilepsy is
correlated with cognitive alterations in memory function in temporal
lobe epilepsy. Most deterioration is seen in patients with long-standing
drug resistant symptomatic left mesial temporal epilepsy.


Neuropsychology, Neuroscience


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Zuletzt aktualisiert 2019-10-08 um 00:15