Regularity analysis of spontaneous MEG activity in attention-deficit/hyperactivity disorder

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Author list: Gómez, C., Poza, J., García, M., Fernández, A., Hornero, R.
Publisher: Department of Signal Theory and Communications, E.T.S. Ingenieros de Telecomunicación, University of Valladolid
Publication year: 2011
Journal: Conference proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference (1557170X)
Volume number: 2011
Start page: 1765
End page: 1768
Number of pages: 4
ISSN: 1557170X
Languages: English-Great Britain (EN-GB)


The aim of this study was to analyze the magnetoencephalography (MEG)
background activity in Attention-Deficit/Hyperactivity Disorder (ADHD)
using a regularity measure: sample entropy (SampEn). Five minutes of
recording were acquired with a 148-channel whole-head magnetometer in 14
ADHD patients and 14 control subjects. Our results showed that ADHD
patients' MEGs were more regular than controls' recordings.
Additionally, there were statistically significant differences (p <
0.01, Student's t-test with Bonferroni's correction) at the five
analyzed brain areas: anterior, central, posterior, left lateral and
right lateral. Using receiver operating characteristic (ROC) curves, the
highest accuracy (82.14%) was achieved at posterior region, whereas the
highest area under the ROC curves (0.8827) were reached at anterior and
central brain regions. These results suggest the usefulness of SampEn
to reveal an abnormal type of dynamics associated with ADHD.


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Last updated on 2019-13-08 at 00:16