Relationship between prepulse inhibition of acoustic startle response and schizotypy in healthy Japanese subjects

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Publication Details

Author list: Canuet L
Publisher: Wiley: 12 months
Publication year: 2010
Journal: Psychophysiology (0048-5772)
Volume number: 45
Issue number: 5
Start page: 831
End page: 837
Number of pages: 7
ISSN: 0048-5772
eISSN: 1469-8986
Languages: English-Great Britain (EN-GB)


Prepulse inhibition (PPI) of the acoustic startle reflex (ASR) is the
most common psychophysiological index of sensorimotor gating. Several
studies have investigated the relationship of PPI of ASR to schizotypy
in Caucasians. However, little has been reported on this relationship in
Asians. We investigated a possible relationship between PPI of ASR and
schizotypy in 79 healthy Japanese subjects. Schizotypy was assessed by
the Schizotypal personality Questionnaire (SPQ). PPI was evaluated at
signal-to-noise ratios (SnRs: difference between background noise
intensity and prepulse intensity) of +12, +16, and +20 dB. The total SPQ
score, cognitive/perceptual score, and interpersonal score correlated
negatively with PPI at SnR of +16 and +20 dB. We conclude that PPI is
associated with the trait of schizotypy in healthy Asian subjects.


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Last updated on 2019-13-08 at 00:45