Maternal coffee intake and associated risk factors: Effects on fetal growth and activity | Consumo de café e factores de risco associados: Efeitos no crescimento e actividade fetal

Journal article


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Publication Details

Author list: Conde A
Publisher: Ordem dos Médicos
Publication year: 2011
Volume number: 24
Issue number: 2
Start page: 241
End page: 248
Number of pages: 8
ISSN: 1646-0758
Languages: English-Great Britain (EN-GB), Portuguese-Portugal (PT-PT)


Empirical studies have shown that fetal growth and activity can be
affected by several risk factors, such as maternal anxiety, depression
and tobacco or alcohol consumption. Caffeine intake has received less
attention in the literature, as well as the analysis of the mutual
interplay of the range of such risk factors. This study aimed to examine
effects of mother's coffee intake and associated risk factors during
early pregnancy on fetal growth and activity. The sample involved 47
fetuses (51.1% male and 48.9% female) with gestational ages between
20-22 weeks whose mothers were recruited in a portuguese antenatal
obstetric unit. Repeated measures of mother's anxiety (STAI-S) and
depression (EPDS) and information about socio-demographics and
substances consumption were collected during the first and second
trimesters of pregnancy. Fetal activity and biometry were measured
during the 2 nd trimester ultrasound. Results showed that 1)
23.4% of the pregnant women (N = 11) had regular coffee intake; 2) no
significant differences were found neither on fetal growth nor on fetal
movements considering mother's coffee intake; 3) when mother's
socio-demographics and substances consumption were considered, tobacco
consumption and anxiety at the 2 nd trimester appeared as significant predictors of fetal growth and mother's coffee intake and anxiety symptoms at the 2 nd
trimester emerged as significant predictors of fetal movements. An
adverse impact of maternal coffee intake during pregnancy was found on
fetal activity but not on fetal growth. A deeper understanding of the
multiple pathways by which these risk factors affect fetal growth and
activity is needed.


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Last updated on 2019-10-08 at 00:30